One of the ways to disprove a theory is to find an exception to it. The person developing the theory may purposely seek the exception. If so, that would be known as a disproof experiment, a purposeful attempt to make a theory fail. Some scientists refrain by stating that it is up to other scientists to find the exceptions that make a theory fail. If however the scientist takes seriously the search for the truth, then the obligation to disprove the theory ought to be felt as a high priority after a theory is established.
The originality theory for the entire universe is a theory supported unanimously by extensive evidence throughout the universe. A skeptic suggested that the theory would fail in the microscopic world because there would be less space to permit originalities. That seemed a sufficient reason to attempt the disproof of the originality theory microscopically.
The first attempt was to investigate the originality of a microscopic plant. Composed of two semicells, Micrasterias is a plant that is about 300 microns in diameter. The study compared the morphology of a sample of 105 Micrasterias cells and their semicells for originality or duplicates and calculated the statistical probabilities. All of the cells and their semicells were originals. There were no duplicates. See the figures above. This attempt to disprove the originality theory failed. And if one were to believe that all Micrasterias and their semicells are originals, then the chances of being wrong would be 1 chance in 1/2^210, less than 1 chance in a vigintillion of chances, enormously beyond what is needed to prove anything statistically. See more details on the way the article originally was published in a science journal in the latest book.